Effects of retinoic acid on ascites cells of the TA3 mouse mammary carcinoma |
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Authors: | E Walker-Nasir J F Codington L A Lampert R W Jeanloz |
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Institution: | (1) Laboratory for Carbohydrate Research, Departments of Biological Chemistry and Medicine, Harvard Medical School and Massachusetts General Hospital, 02114 Boston, MA, USA;(2) Present address: Biogen S.A., Geneva 24, Switzerland |
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Abstract: | Summary Retinoic acid caused a decrease in adhesiveness but no growth change in the allotransplantable TA3-Ha cell and no change in adhesiveness or growth in the strain specific TA3-St cell. The retinoic acid binding protein was detected in the TA3-Ha, but not the TA3-St, cell.This study was supported in pat by Public Health Service Grants CA-08418 and CA-18600 from the National Cancer Institute, National Institutes of Health. This is publication 955 of the Robert W. Lovett Group for the Study of Diseases Causing Deformities. We gratefully acknowledge the contributions of Drs Luigi M. De Luca and Anton M. Jetten of the Laboratory of Cellular Carcinogenesis and Tumor Promotion, National Cancer Institute, National Institutes of Health, Bethesda, MD, without whose help this study would not have been possible. |
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Keywords: | Mouse mammary carcinoma ascites cells retinoic acid cell adhesiveness cell growth |
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