后基因组时代十年志——兼论十年间生命科学的发展及所面临的挑战

   十年前，“人类基因组计划”这一耗资30亿美元、耗时十余年的伟大科学工程完成之际，人们以为得到了揭开自身生命奥秘的天书，生命科学也划时代地进入了后基因组时代。十年间，一方面，人类基因组的后续工作陆续展开，生命科学持续蓬勃发展的态势；另一方面，基因药物却迟迟不能问世，基因产业逐渐沦为泡沫经济。2010年恰逢人类基因组草图完成10周年，回顾十年间生命科学取得的伟大成就，分析生命科学当下面临的挑战，或许更能理清后基因组时代现代生命科学的发展脉络与走势。

The 10th Anniversary of Post-Genomic Era:Review on Developments and Challenges of Life Science

Ten years ago, the International Human Genome Project spent 3 billion dollars for more than a decade to complete the initial draft of the human genome. It was reasonable to consider that the scientists can draw the Map of Life and the life science stepped into post genome era. In the first post genome decade, on the one hand, the success of HGP have generated huge advance in biology science; on the other hand, the genomic medicine was not developed and the critics argued that genomics industry was a “genomics bubble”. Looking back over the past decade of human genomics, a retrospective review on developments and challenges of modern life science maybe promise insight into life science in post genomic era.