| 3-甲基组氨酸三室模型在研究猪骨骼肌蛋白质降解中的应用 |
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| 引用本文： | 施晓丽,郭春华,明道绪. 3-甲基组氨酸三室模型在研究猪骨骼肌蛋白质降解中的应用[J]. 西南民族学院学报(自然科学版), 2004, 30(4): 460-463 |
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| 作者姓名： | 施晓丽 郭春华 明道绪 |
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| 作者单位： | [1]四川农业大学动物营养所，四川雅安625014 [2]西南民族大学生命与科学技术学院，成都610041 |
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| 摘 要： | 3-甲基组氨酸(3MH)主要是动物骨胳肌蛋白分解代谢产物，它不能再用于合成蛋白，因而3MH是研究动物骨胳肌蛋白降解率的一个可行示踪物．将标记的3MH经颈静脉注射，对血液中的同位素丰度进行观测，再根据猪体内3MH代谢特点，构建出猪骨胳肌蛋白降解的三分域模型．本文着重对该模型的的理论基础进行了讨论。
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| 关 键 词： | 三室模型，3-甲基组氨酸 猪 骨胳肌 蛋白降解 |
| 文章编号： | 1003-2843(2004)04-0460-04 |
| 修稿时间： | 2004-05-08 |
Estimation of skeletal muscle protein degradation in pigs by 3-mehtyhistine three pool model analysis |
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| SHI Xiao-li,GUO Chun-hua,MING Dao-xu. Estimation of skeletal muscle protein degradation in pigs by 3-mehtyhistine three pool model analysis[J]. Journal of Southwest Nationalities College(Natural Science Edition), 2004, 30(4): 460-463 |
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| Authors: | SHI Xiao-li GUO Chun-hua MING Dao-xu |
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| Abstract: | 3-mehtyhistine(3MH), the end product of the muscle protein degradation, can not be reutilized for protein synthesis, and, therefore, is thought to be a marker of skeletal muscle protein breakdown. Injected with an intravenous dose of the labeled 3MH, the isotope disappearance in plasma was measured. Based on the analysis of the characteristics of 3-mehtyhistine metabolism of the pig, the paper discusses how to deduce the parameters of the three pool model, and estimate the muscle protein degradation. |
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| Keywords: | three pool model 3-mehtyhistine skeletal muscle protein degradation pig |
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