Multifunctions of histone H1 proteins |
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| Authors: | Wenjun Wang Ruiqi Cai Hongdou Xiao Ling Zheng |
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| Affiliation: | 1. College of Life Sciences, Wuhan University, Wuhan, 430072, Hubei, China
2. Diabetes Center, Wuhan University, Wuhan, 430072, Hubei, China
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| Abstract: | Among various histones, histone H1 proteins have been appreciated for their multiple functions in diverse biological processes. In addition to being a structural protein in chromatin, H1 proteins also play critical roles in cell cycle, gene expression, and development. Recent studies reveal the possible effects of H1 in some diseases, such as cancer and neurodegenerative diseases. Here, we review different variants of H1, the functions, and post translational modifications of H1 variants are also discussed. |
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