| Non-viral gene delivery carrier of probe type host molecule ——Interactions between DNA and β-cyclodextrin derivative complexes (I) |
| |
| 作者姓名： | LIU Tao CHEN Long HOU Sen XUE Yonglai FENG Xizeng |
| |
| 作者单位： | Key Laboratory of Bioactive Materials, Ministry of Education, Collegeof Life Science, Nankai University, Tianjin 300071, China |
| |
| 基金项目： | Acknowledgements The authors would like to thank Dr. and Prof. Lee Im Shik for his generous help in molecular dynamic calculation. This work was supported by the National Natural Science Foundation of China （Grant No. 90403140）, the Tianjin Natural Science Foundation （Grant No. TJ043801111）, and the Scientific Research Foundation for the Returned 0verseas Chinese Scholars, Ministry of Education of China （Grant No. B04970）. |
| |
| 摘 要： | GENE THERAPY IS A COMMON PROCESS TO DELIVER EXTRIN- SIC GENES INTO TARGET CELLS FOR FURTHER GENE EXPRESSION, FOR THE PURPOSE OF TREATING DISEASES. A WELL DESIGNED GENE DELIVERY CARRIER CAN EFFICIENTLY PACKAGE AND PRO- TECT NUCLEIC ACID FROM BEING DIGESTED BY A VARIETY OF ENZYMES IN VIVO AND SHOULD BE ABLE TO SPECIFICALLY LO- CATE EXTRINSIC GENES INTO THE TARGET ORGANISMS. S…
|
| 关 键 词： | phenanthroline-β-cyclodextrin derivatives (DZY-1) λ-DNA non-virus gene delivery carrier agarose gel electrophoresis scanning electron microscope (SEM). |
| 收稿时间： | 2005-08-30 |
| 修稿时间： | 2005-08-302005-10-31 |
| 本文献已被 CNKI 维普 SpringerLink 等数据库收录！ |
| 点击此处可从《科学通报(英文版)》浏览原始摘要信息 |
|
点击此处可从《科学通报(英文版)》下载全文 |
