生命科学用原子力显微镜之原理与应用

本文在简单介绍原子力显微镜（AFM）成像原理及其特点的基础上，主要从AFM对核酸、蛋白质和细胞微生物的表面特性、内部结构、分子细胞间的相互作用及其动态观察、单分子操纵以及分子识别等方面的应用加以举例介绍。随着科学技术的发展，AFM的不断改进与完善，AFM必将成为生命科学研究的重要手段之一。

A New Atomic Force Microscope for Life Science

Basis on the imaging theory and characterizations of atomic force microscope(AFM),its implications with some examples in surface properties and internal structure of nuclear,protein,cell and microorganism,and its interactions between molecules or cells and its dynamic observation,single molecular manipulation,molecular recognition,and so on,are introduced in this paper.With the development of science and technology,through the improving of AFM self,we believe AFM must become one of powerful tools in life science research.