| 含氮芳环氢化及N-烷基化反应的研究——1-烷基-2-(2,2-二环己基乙基)哌啶盐的合成 |
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| 引用本文： | 眭云龙,李良助.含氮芳环氢化及N-烷基化反应的研究——1-烷基-2-(2,2-二环己基乙基)哌啶盐的合成[J].北京大学学报(自然科学版),1992(6). |
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| 作者姓名： | 眭云龙 李良助 |
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| 作者单位： | 北京大学化学系
(眭云龙)，北京大学化学系(李良助) |
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| 摘 要： | 2-(2,2-二苯乙烯基)吡啶在醇(ROH)溶剂中以钯—炭为催化剂,在催化氢化条件下发生氢化和N-烷基化反应,再与酸作用生成1—烷基-2-(2,2-二环己基乙基)哌啶盐。应用8个不同的饱和醇(ROH)作溶剂,分别合成了8个相应的化合物。讨论了反应的历程。
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| 关 键 词： | 催化氢化 催化脱氢 N-烷基化 |
Study on Hydrogenation and N-alkylation of Aromatic Ring with a Nitrogen-Synthesis of 1-alky1-2-(2, 2-dicyclohexylethyl) piperidinium Salts |
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| SUI Yunlong,LI Liangzhu.Study on Hydrogenation and N-alkylation of Aromatic Ring with a Nitrogen-Synthesis of 1-alky1-2-(2, 2-dicyclohexylethyl) piperidinium Salts[J].Acta Scientiarum Naturalium Universitatis Pekinensis,1992(6). |
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| Authors: | SUI Yunlong LI Liangzhu |
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| Abstract: | 2-(2, 2-diphenylethenyl) pyridine underwent hydrogenation and N-alkylation under the condition of catalytic hydrogenation in the presence of an alcohol (ROH) as the solvent and Pd-C as a catalyst, and then reacted with an acid to form l-alkyl-2-(2, 2-dicyclohexylethyl) piperidinium salt. Using eight saturated alcohols as the solvents produced eight compounds separately. The reaction mechanism was discussed. |
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| Keywords: | Catalytic hydrogenation Catalytic dehydrogenation N-alkylation |
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