Bacterial utilization of cyclo(glycyl-L-prolyl) |
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| Authors: | E Adams D A Blass J B Harford J A Adams |
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| Institution: | (1) Department of Biological Chemistry, University of Maryland School of Medicine, 21201 Baltimore, Maryland, USA |
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| Abstract: | Summary 3 strains of soil bacteria (2Achromobacter, 1Flavobacterium) were isolated by growth on cyclo(Gly-L-Pro) as carbon/nitrogen source. Good growth required yeast extract supplements. Utilization of cyclo(Gly-L-Pro) was inducible. Many efforts failed to obtain active cell-free preparations. Injected radioactive cyclo(Gly-L-Pro) was excreted intact by the albino rat; in contrast, injected radioactive H-Gly-L-Pro-OH was extensively metabolized.Supported by Grant GM-11105 from the National Institutes of Health. |
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