Ein fluoreszenzmarkiertes Physalaemin-Analoges mit hoher biologischer Aktivität |
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Authors: | B. Mehlis H. Apelt J. Bergmann H. Niedrich P. Oehme |
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Affiliation: | (1) Institut für Pharmakologie, Deutsche Akademie der Wissenschaften zu Berlin, 1115 Berlin-Buch, DDR |
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Abstract: | Summary The synthesis of fluorescent labelled derivative of the N-terminal physalaemin hexapeptide [6–11], which contains a 1-dimethylaminoaphtalene-5-sulfonyl residue at the -amino group of the N-terminal Lysine, is described. Pharmacological data of the fluorescent labelled compound as compared with the unsubstituted peptide are reported. |
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