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Dipeptidyl aminopeptidase in neonatal rat brain regions
Authors:K. Imai  T. Kato
Affiliation:(1) Department of Oral Biochemistry, Kanagawa Dental College, 238 Yokosuka, (Japan);(2) Laboratory of Cell Physiology, Department of Life Chemistry, Graduate School at Nagatsuta, Tokyo Institute of Technology, 227 Yokohama, (Japan)
Abstract:Summary Changes in the activity of dipeptidyl aminopeptidase in rat pituitary gland and various brain regions were examined at 3, 5 and 20 weeks of age. The enzyme activity per g tissue wet weight in pituitary gland was the highest of all tissues studied. Subcellular distribution of the activity was also studied. The highest enzyme activity was found in a crude mitochondrial fraction including synaptosomes.
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