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Ventricular fibrillation threshold during acute ischemia in hypertrophied rat hearts
Authors:T Kohya  S Kimura  R J Myerburg  A L Bassett
Institution:(1) Departments of Pharmacology and Medicine, University of Miami School of Medicine, 33101 Miami, Florida, USA
Abstract:Summary Ventricular fibrillation threshold was significantly lower in hypertrophied hearts than in normal hearts. Ischemia produced by coronary occlusion reduced fibrillation threshold in both normal and hypertrophied hearts, but the maximum reduction in fibrillation theshold was observed earlier in hypertrophied hearts.
Keywords:Ventricular fibrillation threshold  cardiac hypertrophy  pressure overload  ischemia
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