Qualitative and quantitative relationships between affinity constants from model study and real adsorption data

Linear polymers bearing the same functional groups as their corresponding adsorbents could be used as models to study the ad-sorption behaviors. However, the relationships between the data from model study and real adsorption have not been fully interpreted. In this work, three adsorbent (CP1-Zn²⁺, CP2-Zn²⁺ and CP3-Zn²⁺) and their corresponding linear models (P1-Zn²⁺, P2-Zn²⁺ and P3-Zn²⁺) were synthesized. The affinity constants (Ka) between these models and target peptide DFLAE (DE5) were obtained by isothermal titration calorimetry (ITC). Adsorption capacities and adsorption affinities were carried out by static adsorption and adsorption isotherm. The qualitative and quantitative relationships between affinity constants from model study and the real ad-sorption data were explored. This study was significant to bridge the model study with the real adsorption.