| 磷酸川芎嗪注射液安全性试验研究 |
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| 引用本文： | 王小蒙,邢增术,符健.磷酸川芎嗪注射液安全性试验研究[J].海南大学学报(自然科学版),2004,22(4):352-354. |
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| 作者姓名： | 王小蒙 邢增术 符健 |
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| 作者单位： | 海南医学院,药理学教研室,海南,海口,571101;海南医学院,药理学教研室,海南,海口,571101;海南医学院,药理学教研室,海南,海口,571101 |
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| 摘 要： | 为了评价磷酸川芎嗪注射液的安全性,笔者采用过敏试验、静脉血管刺激试验、肌肉刺激试验、溶血试验进行动物药理实验研究.结果表明:质量浓度为0.0012g·mL-1的磷酸川芎嗪注射液对动物无过敏反应,无溶血现象,对静脉血管、肌肉无刺激反应,提示该药在本实验条件下是安全的.
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| 关 键 词： | 磷酸川芎嗪注射液 安全性试验 评价 |
| 文章编号： | 1004-1729(2004)04-0352-03 |
| 修稿时间： | 2004年7月16日 |
Experimental Study on the Safety of Lingustration Phosphate for Injection |
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| WANG Xiao-meng,XING Zeng-shu,FU Jian.Experimental Study on the Safety of Lingustration Phosphate for Injection[J].Natural Science Journal of Hainan University,2004,22(4):352-354. |
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| Authors: | WANG Xiao-meng XING Zeng-shu FU Jian |
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| Abstract: | To evaluate the safety of the lingustration phosphate for injection, a pharmacological study was made by the allergy test,venous and muscular stimulation test, and the hemolytic test. These results showed that the injection with 0.001 2 g lingustration phosphate per ml. had no allergy effect and the hemolytic phenomenon on animals, no significant stimulation effect on vessels and muscles.These suggested that the drug be safe under the experimental condition. |
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| Keywords: | lingustration phosphate for injection test for safety evaluation |
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