基于金纳米的第3代平面型葡萄糖传感器的研究

在制备亲水金纳米颗粒的基础上，与明胶一起固定葡萄糖氧化酶（GOD），制得具有纳米增强效应的葡萄糖传感器。实验表明：纳米颗粒能够大幅度地提高固定酶的催化活性，提高响应灵敏度，且电极响应迅速，一般在5s之内就能测得稳定的电流响应值。讨论了纳米颗粒在酶固定化及其对葡萄糖响应中所起的作用，为基于直接电子传递的第3代生物传感器折研制和开发、以及扩展纳米颗粒的应用领域提供了技术参考信息。

An Au Nanoparticles Modeified Planar Glucose Sensor

A glucose sensor based on planar platinum electrode modified by Au nano particles was reported. Glutin used in the immobilization of glucose oxidase could greatly improve the activity of the immobilized enzyme. The characterizations of Pt/nano-Au/GOD sensor have been investigated. The results show that the response time is 5s, faster than others reported, and a linear range of 0-12 mmol/L. The response mechanism of sensor modified with Au nano particles was disscused. The present results provided some infonnation for the development of the third generation of sensor.