Marine antitumor agents: 14-deoxycrassin and pseudoplexaurol,new cembranoid diterpenes from the Caribbean gorgonianPseudoplexaura porosa |
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| Authors: | A D Rodríguez N Martínez |
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| Institution: | (1) Department of Chemistry, P.O. Box 23346, U.P.R. Station, University of Puerto Rico, Río Piedras, 00931-3346 Puerto Rico, Puerto Rico, USA |
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| Abstract: | Two new cytotoxic antitumor diterpenoids of the cembrane class, named 14-deoxycrassin (3) and pseudoplexaurol (4), have been isolated from the Caribbean gorgonian octocoralPseudoplexaura porosa. The structure of lactone3, possessing the infrequently encountered  -methylene- -lactone ring, has been established from spectral and chemical data and that of alcohol4 has been established from spectral data. |
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| Keywords: | Gorgonian antitumor agent cembranoid diterpene Pseudoplexaura porosa |
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