干细胞与再生医学发展前瞻

 干细胞与再生医学是当今生命科学领域研究的前沿与热点。近年来，涌现出一系列突破性的研究成果，将干细胞研究推向新的历史阶段，为再生医学的发展带来深刻变革。本文分析体内外不同来源的干细胞在再生医学的治疗应用、小分子化合物在细胞命运转变机理研究和功能性细胞获取方面的研究现状与前景，讨论了干细胞与再生医学在临床治疗应用的安全性与规范性。

Perspective of stem cell and regenerative medicine

Recently, a series of breakthroughs in stem cell and regenerative medicine, as the frontier and the hotspot of life sciences, brings numbers of revolutionary changes into the medical development. In this paper, we mainly summarize and analyze the current progresses and perspectives of the applications of stem cells from distinct resources in vitro and in vivo for the regenerative treatment and the roles of small molecules in the mechanisms involved in the cell fate transition and the functional cells obtained in vitro. Meanwhile, the safety and the regulation of the applications of the stem cell and regenerative medicine in the clinical therapy are discussed, to provide some food for thought for reasonable arrangements and plots in this field.