Abstract: | 3 nonionic detergents, Triton X-100, Lubrol WX and NP-40, inhibited binding of 3H]-ATII to bovine adrenocortical plasma membranes. This effect appeared to be direct and not due to solubilization of the ATII receptor by these agents. Sodium deoxycholate and the chaotropic ions, ClO4- and Br-, produced effects similar to the nonionic detergents. |