| 水杨醛谷氨酸Schiff碱配体及其金属配合物的制备与抑菌活性研究 |
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| 引用本文： | 张丽影,赵小菁,齐小辉,那立艳.水杨醛谷氨酸Schiff碱配体及其金属配合物的制备与抑菌活性研究[J].大连民族学院学报,2010,12(3):196-198. |
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| 作者姓名： | 张丽影 赵小菁 齐小辉 那立艳 |
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| 作者单位： | 大连民族学院,生物化学工程国家民委-教育部重点实验室,辽宁,大连,116605 |
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| 摘 要： | 合成出水杨醛谷氨酸（Sal—Glu）Schiff碱配体及其6种金属配合物，采用红外光谱及紫外光谱对其进行了表征，并进行了抑菌实验。结果表明，配体中C=N中的氮原子以及C-O（酚氧）中的氧原子参与了对金属离子的配位作用，配体及配合物均对大肠杆菌具有抑制作用，其中Sal—Glu—Fe对大肠杆菌的抑菌活性最好，抑菌圈直径最大。
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| 关 键 词： | Schiff碱配体 金属配合物 抑菌活性 |
Preparation and Antibacterial Activity of Salicylaldehyde Glutamic Acid Schiff Base Ligand and Its Metal Complexes |
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| ZHANG Li-ying,ZHAO Xiao-jing,QI Xiao-hui,NA Li-yan.Preparation and Antibacterial Activity of Salicylaldehyde Glutamic Acid Schiff Base Ligand and Its Metal Complexes[J].Journal of Dalian Nationalities University,2010,12(3):196-198. |
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| Authors: | ZHANG Li-ying ZHAO Xiao-jing QI Xiao-hui NA Li-yan |
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| Institution: | ZHANG Li - ying, ZHAO Xiao - jing, QI Xiao - hui, NA Li - yan ( Biochemical Engineering, State Ethnic Mfairs Commission and Ministry of Education, Dalian Nationalities University, Dalian Liaoning 116605, China) |
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| Abstract: | We synthesized salicylaldehyde glutamic acid Schiff base ligand and its six metal com- plexes and characterized them using infrared and ultraviolet spectra, along with antibacterial tests. The results show that nitrogen atoms in the C = N group and oxygen atoms in the C -0 group （phenolic oxygen） are all involved in the coordination of metallic ions and that both the ligand and the complexes have antibacterial activity against E. coli. Among them, Sal -Glu - Fe has the best antibacterial activity as it has the largest inhibition zone diameter. |
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| Keywords: | Schiff base ligand metal complex antibacterial activity |
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