Prostaglandin E2 increases mechanically evoked potentials in the peripheral nerve |
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| Authors: | S. Pateromichelakis J. P. Rood |
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| Affiliation: | (1) Department of Oral and Maxillofacial Surgery, King's College Hospital Dental School, Denmark Hill, SE5 8RX London, (England) |
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| Abstract: | ![]()
Summary Subdermal injections of PGE2 (5  g) in the rat foot lead to increases in the potentials evoked in sensory nerve branches by the mechanical stimulation of the skin. This sensitization of both A and C fibres complements the previously described hyperalgesic effects of prostaglandins of the E series. |
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