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New phytotoxic butenolides produced bySeiridium cardinale,the pathogen of cypress canker disease
Authors:L. Sparapano  A. Evidente  A. Ballio  A. Graniti  G. Randazzo
Affiliation:(1) Dipartimento di Patologia vegetale, University of Bari, Bari, (Italy);(2) Dipartimento di Chimica organica e biologica, University of Naples, Naples, (Italy);(3) Istituto di Chimica biologica, La Sapienza' University of Rome, Rome, (Italy)
Abstract:Summary Two new butenolides, seiridin andiso-seiridin, were isolated from culture filtrates ofSeiridium cardinale, the pathogen of cypress canker, a destructive disease ofCupressus and relatedConiferae These metabolites were characterized as 3-methyl-4-(2-hydroxyheptyl)-2(5H)-furanone and its 4-(3-hydroxyheptyl) isomer, respectively. Chlorotic, and necrotic symptoms were produced on leaves of either host or non-host test plants by absorption of 0.3 mg/ml solutions of either compound. These also showed antibacterial activity.This study was supported in part by the National Research Council, Rome (special ad hoc project lsquoChimica fine e secondariarsquo) and in part by the Ministry of Education, Rome.
Keywords:Seiridium cardinale  cypress canker  seiridin  iso-seiridin  butenolides  phytotoxins  antibiotics
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