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一种简单合成氨基葡聚糖保护的金颗粒的方法
引用本文:吕晓丽,王大鹏,康立娟,孙德武.一种简单合成氨基葡聚糖保护的金颗粒的方法[J].松辽学刊,2006,27(1):68-69.
作者姓名:吕晓丽  王大鹏  康立娟  孙德武
作者单位:[1]吉林农业大学资源与环境学院,吉林长春130118 [2]吉林师范大学化学学院,吉林四平136000
摘    要:采用氨基-葡聚糖(AD)保护的金颗粒作为灵敏的光学探针来检测外源凝集索伴刀豆球蛋白A(ConA)是一种正在发展中的检测方法.AD保护的金颗粒通过采用氨基-葡聚糖直接还原的方法制备,氨基-葡聚糖既为还原剂又是保护剂,金纳米颗粒的尺寸可以通过改变AD用量来调节.在中性环境下,AD与ConA以4:1的比率结合形成Au-ConA复合物,并且ConA引起颗粒的聚集.

关 键 词:氨基-葡聚糖    纳米颗粒
文章编号:1000-1840-(2006)01-0068-02
收稿时间:01 3 2006 12:00AM
修稿时间:2006年1月3日

A Facile Method for the Synthesis of Amino-dextran Protected Gold Nanoparticles
LU Xiao-li,WANG Da-peng,KANG Li-juan,SUN De-wu.A Facile Method for the Synthesis of Amino-dextran Protected Gold Nanoparticles[J].Songliao Journal (Natural Science Edition),2006,27(1):68-69.
Authors:LU Xiao-li  WANG Da-peng  KANG Li-juan  SUN De-wu
Institution:1. College of Resources and Environment,Jilin A gricultural University,Changchun 130118,China;2.College of Chemistry,Jilin Normal Univerity,Siping 136000,China
Abstract:A sensitive method for the detection of thelectin protein concanavalin A(Con A)was developed using amino-dextran(AD)-protected gold(AD-Au)as sensitive optical probes.The AD-Au were synthesized by directly applying amino-dextran as a reductive and protective reagent.The size of the nanoparticles could bealtered by changing the molar ratio of AD to the metal salt.salt.The amino-dextran bound to Con A by forming a 4:1 Au-Con A complex at neutral pH,and the nanoparticles were induced to aggregate by Con A.
Keywords:Amino-dextran  Gold  nanoparticles
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