| 4-苯基-4-(1,2,4-三唑-1-基)-3-丁烯-2-酮及其衍生物的合成 |
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| 引用本文： | 黄龙祥,吕春绪.4-苯基-4-(1,2,4-三唑-1-基)-3-丁烯-2-酮及其衍生物的合成[J].南京理工大学学报(自然科学版),2003,27(1):110-112. |
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| 作者姓名： | 黄龙祥 吕春绪 |
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| 作者单位： | 南京理工大学化工学院,南京,210094 |
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| 摘 要： | 4－苯基－4－（1，2，4－三唑－1－基）－3－丁烯－2－酮可由3－溴－4－氯－4－苯基－2－丁酮在碱性条件下与1，2，4－三唑反应以71．4％的产率制得。其反应机理由实验和质谱证明是一个先消除氯化氢的三步反应过程，制备出了其衍生物4－苯基－4－（1，2，4－三唑－1－基）－3－丁烯－2－醇和和4－苯基－4－（1，2，4－三唑－1－基）－2－甲氧基－3－丁烯。测试结果表明，这些化合物具有较好的杀菌活性。
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| 关 键 词： | 4－苯基－4－（1 2 4－三唑－1－基）－3－丁烯－2－酮 合成 杀菌活性 杀菌剂 唑类化合物 取代唑类衍生物 |
| 修稿时间： | 2000年4月5日 |
Preparation of 4-Pheny-4-(1,2,4-Triazole-1-yl)-3-Buten-2-One and Its Derivatives |
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| HuangLongxiang,LuChunxu.Preparation of 4-Pheny-4-(1,2,4-Triazole-1-yl)-3-Buten-2-One and Its Derivatives[J].Journal of Nanjing University of Science and Technology(Nature Science),2003,27(1):110-112. |
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| Authors: | HuangLongxiang LuChunxu |
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| Abstract: | pheny-4-(1,2,4-triazole-1-yl)-3-buten-2-one was prepared from 3-bromo-4 -chloro-4-phenyl-3-buten-2-one by a yield of 71.4%. Its reaction mechanism had been proved to be a three steps reaction, elimination of HCl is the first step, by the experimental results and MS data. Its derivatives 4-phenyl-4-(1,2,4-triazole-1-yl)-3-buten-2-ol and 4-phenyl-4-(1,2,4-triazole-1-yl) -2-methoxy-3-butene were also prepared. The testing outcomes showed they had good fungicidal activity. |
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| Keywords: | ketemes mechanism preparation fungicidal activities |
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