| 青蒿素的制备、用途和展望 |
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| 引用本文： | 阮栋梁,王丰玲,张英锋,郑向军. 青蒿素的制备、用途和展望[J]. 渤海大学学报(自然科学版), 2007, 28(2): 108-112 |
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| 作者姓名： | 阮栋梁 王丰玲 张英锋 郑向军 |
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| 作者单位： | 香港大学,化学系;河北省秦皇岛市第一中学,河北,秦皇岛,066000;北京师范大学,化学系,北京,100875 |
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| 摘 要： | 青蒿素是含有过氧桥的新型倍半萜内酯，其衍生物有青蒿琥酯、蒿甲醚和二氢青蒿素等。青蒿素是有效的疟痰治疗药物，此外它还具有抗肿瘤、抗寄生虫、影响免疫等药理作用。对青蒿素及其衍生物进行了综述。
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| 关 键 词： | 菁蒿素 抗疟疾 药理作用 |
| 文章编号： | 1673-0569（2007）02-0108-05 |
| 修稿时间： | 2007-04-06 |
Preparation application and prospect of artemisinin |
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| RUAN Dong-liang,WANG Feng-ling,ZHANG Ying-feng,ZHENG Xiangjun. Preparation application and prospect of artemisinin[J]. Journal of Bohai University:Natural Science Editio, 2007, 28(2): 108-112 |
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| Authors: | RUAN Dong-liang WANG Feng-ling ZHANG Ying-feng ZHENG Xiangjun |
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| Affiliation: | 1. Depart ment of Chemistry, Hong Kong University, China ;2. No. 1 High School in Qinhuangdao City of Hebei Province,Qinhuangdao 066000,China ;3. Department of Chemistry,Beijing Normal University 100875 ,China |
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| Abstract: | Artemisinin with an endoperoxide function was derived from artemisia by Chinese research workers in 1972. Its derivatives include artesunate, artemether, dihydroartemisinin etc. Artemisinin,which is the most effective antimalarial drug,has other pharmacological activity such as antitumor ,antischistosome,affecting immunity etc. This article summarizes the research progress of artemisinin and its derivatives to provide references for the expoitation and utilization. |
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| Keywords: | artemisinin antimalarial pharmacological activity |
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