胎儿肝脏的形态学研究

187例河南地区胎儿肝重、体重被测量,并用光镜观察肝的组织发生。结果表明:肝重(y)与体重(x)有显著的正相关关系,相关系数为0.9861,回归方程 =-0.0367+0.0417x;肝重随胎龄(x)变化的回归方程 =1.772e~(0.4359x);15-20周肝细胞渐排列为细长的索;23周以前肝中造血细胞(HC)甚多,24周肝血窦中HC数量减少,故肝中HC量减少时的顺序是先血窦后窦周隙;35周时各处HC数量大大减少,这提示,肝造血功能于35周急骤下降。

Morphological Study on the Liver of Human Fetus

The body and liver weights of 136 fetuses collected in Henan Province were measured,and the liver histogenesis was observed under light microscope.The statistical anaysis showed that therewas a significant positive linear regression between the body and liver weight,the coefficient of correlationwas 0.9861 and the equation was ()=-0.0367+0.0417x(x-body weight),and the liver weight related withthe age of fetus exponentially with the equation,()=1.772e~(0.4359x)(x-age).In 15-week-old fetus,the hepaticcells were separated into cell masses by hematopoietic cells and sinusoids;In 20-week-old fetus,the livercells formed hepatic cords which composed of 1-2 rowls of cells.Hematopoietic cells were present in allfetus from 15 to 35-week,especially in thoso before 23 weeks.The decrease of hematopoietic cells occuredfirst from sinusoids,then perisinusoidal spaces.The hematopoietic function decreased abruptly in35-week-old fetus.