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Increase of collagen synthesis in pulmonary arteries of monocrotaline-treated rats |
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| Authors: | R Kameji H Otsuka Y Hayashi |
| Abstract: | Collagen synthesis in the pulmonary artery in animals with pulmonary hypertension was studied using monocrotaline-treated rats as a model. Incorporation of 14C-lateled proline into collagenase-digestible protein in the pulmonary artery was found to be 4-5 times higher in monocrotaline-treated rats than in control rats. |
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