Investigations into the effects of ACTH on the half-life of mitochondrial proteins in the rat adrenal cortex |
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| Authors: | G. Neri A. M. Gambino G. Mazzocchi G. G. Nussdorfer |
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| Affiliation: | (1) Department of Anatomy, University of Padua, I-35100 Padua, (Italy) |
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| Abstract: | Summary ACTH elongates the half-life of the mitochondrial proteins from the rat adrenal cortex, and chloramphenicol inhibits this effect of ACTH. The hypothesis is advanced that the ACTH-provoked stabilization of the adrenocortical mitochondrial proteins requires continuous mitochondrial DNA-dependent protein synthesis. |
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