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| 南中国海红树林海洋真菌2492号次级代谢产物研究 | |
| 引用本文： | 王军,佘志刚,姜广策,林永成,L.L.P.Vrijmoed.南中国海红树林海洋真菌2492号次级代谢产物研究[J].中山大学学报(自然科学版),2005,44(2):132-134. |
| 作者姓名： | 王军 佘志刚 姜广策 林永成 L.L.P.Vrijmoed |
| 作者单位： | 1. 中山大学药学院,广东,广州,510080 2. 中山大学化学和化学工程学院,广东,广州,510275 3. 香港城市大学生物学和化学系,香港 |
| 基金项目： | 国家高技术研究发展计划(863计划)，广东省自然科学基金 |
| 摘 要： | 研究了来自香港海红树林Phragmites australi的海洋真菌2492号的次级代谢产物.用乙酸乙酯对该菌的培养液进行了液-液萃取,用硅胶柱层析法对提取物进行分离纯化,并用IR,MS,UV NMR波谱法推导确定了单离到化合物的结构.结果在发酵液中分离纯化得到4个有生物活性的生物胺,分别是Hypoxylin A(2),Hypoxylin B(1),N-乙酰酪胺(3)和2492-1(4). |
| 关 键 词： | 海洋真菌 代谢产物 生物胺 |
| 文章编号： | 0529-6579(2005)02-0132-03 |
| 修稿时间： | 2005年2月12日 |
The Secondary Metabolites of the Marine Fungus No.2492 from the Mangrove Phragmites Australi of the South China Sea |
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| WANG Jun,SHE Zhi-gang,JIANG Guang-ce,LIN Yong-cheng,L.L.P.Vrijmoed.The Secondary Metabolites of the Marine Fungus No.2492 from the Mangrove Phragmites Australi of the South China Sea[J].Acta Scientiarum Naturalium Universitatis Sunyatseni,2005,44(2):132-134. | |
| Authors: | WANG Jun SHE Zhi-gang JIANG Guang-ce LIN Yong-cheng LLPVrijmoed |
| Abstract: | The secondary metabolites of the marine fungus No.2492 isolated from the mangrove Phragmites australi of Hong Kong were studied.The growth media of the marinederived fungus was extracted with ethyl acetate ,and the crude extract was isolated by a series of chromatographic steps, which led to the isolation of four known biogenic amines with bioactiviting: hypoxylin A(2), hypoxylin B(1), N-acetyltyramine and 2492-1(4).Their structures were elucidated by spectroscope including FABMS, IR,UV, NMR. |
| Keywords: | marine fungus metabolites biogenic amines |
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