以新换旧--用独立通风笼盒(IVC)取代弹性薄膜隔离器

独立通风笼盒是应生物密封标准不断提高的需要而发明的。这些笼盒为动物提供了一个密封的环境 ,并且对空气携带的污染物的阻断也有很大的帮助。由于转基因动物增多 ,独立通风笼盒应用越来越广泛。它能有效地预防交叉污染 ,并且能可不同来源的动物住在一块 ,而不需要考虑它们的健康状况。本篇将对独立通风笼盒和弹性薄膜隔离器做一个比较。传统的弹性薄膜隔离器被用来把健康状况已经明确的动物放在一起 ,如 ,悉生动物和无菌动物。隔离器是二战时期特雷克斯勒和雷尼尔为研究恙虫病时发明的。如今 ,用隔离器来给动物提供住处经常会遇到这样的问…

Out with The Old-in with New -- Have Flexible Film Isolators Been Superceded by Individual Ventilated Cages(IVCs)?

In response to the needs for improved standards of bio-containment, individual ventilated cages (IVCs) have been developed. These cages provide a protected environment for animals and are of great assistance in containing airborne contaminants. As the number of transgenic animals has increased, IVCs have become more popular because of the possibilities they offer in the prevention of cross-contamination and their capability to house small groups of animals of differing sources in close proximity without compromising their health status.This paper will compare IVCs with flexible film isolators. Historically flexible film isolators have been the method of choice for housing animals of a defined health status such as gnotobiotic and germ free animals. The isolator was devel oped by Trexler and Reyniers during World War Ⅱ for the study of scrub typhus. Today the perception of using isolators for animal housing is still often met with the assumption that isolators are difficult to use and expensive to operate.At B&K Universal Limited we use both isolators and IVCs depending on the particular need. This paper will present a practical comparison of the two methods of containment.