The inhibition of cathepsin B by plasma haptoglobin biochemistry (enzymes,metabolism) |
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| Authors: | N. A. Kalsheker A. R. Bradwell D. Burnett |
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| Affiliation: | (1) Department of Clinical Biochemistry, Addenbrooke's Hospital, Hills Road, CB2 2QR Cambridge, (England);(2) Department of Immunology, Medical School, University of Birmingham, Birmingham, (England) |
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| Abstract: | ![]()
Summary Purified haptoglobin partially inhibits the activity of a lysosomal thiol proteinase, cathepsin B. This inhibition is reversible in the presence of monospecific antiserum to haptoglobin.This work was supported by an East Anglian Regional Health Authority Grant. |
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