| 大鼠肝大部分切除对血及肝组织中cAMP、ATP含量变化的影响 |
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| 引用本文： | 曲娴,胡尚嘉,芦淑芹,吕俊华.大鼠肝大部分切除对血及肝组织中cAMP、ATP含量变化的影响[J].北华大学学报(自然科学版),1998(3). |
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| 作者姓名： | 曲娴 胡尚嘉 芦淑芹 吕俊华 |
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| 作者单位： | 吉林医学院生理教研室!吉林132001(曲娴，胡尚嘉，芦淑芹)，吉林医学院药理教研室(吕俊华) |
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| 摘 要： | 目的：观察大鼠大部分肝切除后3天时血浆及肝组织中cAMP、ATP含量变化与肝再生的影响。方法：用液体闪烁计数仪和高效液相色谱仪分别测定cAMP及ATP含量。结果：大鼠大部分肝切除后血中和肝组织中cAMP含量明显高于正常对照组，肝组织ATP含量也明显增高，与肝重增长呈明显正相关关系。结论：肝再生时许多物质参与调控，可能与cAMP的传递密切相关，同时与能量代谢也有一定的关系。
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| 关 键 词： | 肝切除 cAMP ATP |
The influence of subtotal hepatectomy on the contents of cAMP and ATP in blood and liver of the rats |
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| Qu xian, In Junhua et al.The influence of subtotal hepatectomy on the contents of cAMP and ATP in blood and liver of the rats[J].Journal of Beihua University(Natural Science),1998(3). |
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| Authors: | Qu xian In Junhua |
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| Abstract: | Objective To observe the influence of the changes in cAMP and ATP contents in plasma and liver on hepatic regeneration 3 days following subtotal hepatectomy . Method:The contents of cAMP and ATP were determined respectively with liquid scintillator and high effective liquid chromatograph. Results:The contents of CAMP in blood and liver tissue of rats after subtotal hepatectomy were significantly higher than those in normal control group. There was also a significant increase in ATP content in liver, whick was positively correlated to the increase in liver weight. .Conclusion: There are many substances participating in the regulation and control of liver regeneration, which is closely related to the transimisson through cAMP and meanwhile related to energy metabolism to a certain degree. |
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| Keywords: | hepatectomy cAMP ATP |
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