A specific GT1 ganglioside-luteinizing hormone interaction induces conductance changes in lipid bilayers |
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| Authors: | P. Chatelain M. Deleers A. Poss J. M. Ruysschaert |
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| Affiliation: | (1) Laboratoire de Chimie-Physique des Macromolécules aux Interfaces, Université Libre de Bruxelles, C.P. 206/2, B-1050 Bruxelles, Belgium |
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| Abstract: | ![]()
Summary A specific interaction was demonstrated between GT1 gangliosides incorporated in bilayer membranes and luteinizing hormone. This interaction would allow the penetration of a hormone subunit in the membrane. The results are discussed in terms of adenylate cyclase activation. |
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