| 注射DGAVP后小鼠脑内突触前后结构变化的比较 |
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| 引用本文： | 吴馥梅,萧信生.注射DGAVP后小鼠脑内突触前后结构变化的比较[J].南京大学学报(自然科学版),1992,28(3):418-422. |
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| 作者姓名： | 吴馥梅 萧信生 |
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| 作者单位： | 南京大学生物学系，南京大学生物学系，南京大学生物学系，南京大学生物学系，南京大学生物学系 |
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| 摘 要： |
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| 关 键 词： | DGAVP 学习记忆 突触结构 |
THE COMPARISON BETWEEN PRE-AND POST-SYNAPTIC ULTRASTRUCTURAL CHANGES IN THE BRAIN OF MICE TREATED WITH DGAVP |
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| Wu Fumei Xiao Xinsheng Qian fang Luo Lan and Lu Haxin.THE COMPARISON BETWEEN PRE-AND POST-SYNAPTIC ULTRASTRUCTURAL CHANGES IN THE BRAIN OF MICE TREATED WITH DGAVP[J].Journal of Nanjing University: Nat Sci Ed,1992,28(3):418-422. |
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| Authors: | Wu Fumei Xiao Xinsheng Qian fang Luo Lan and Lu Haxin |
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| Institution: | Department of Biology |
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| Abstract: | This experiment is the further investigation of the synaptic mechanism of DGAVP facilitating memory consolidation on the basis of previous studies. Gray's type I synapses in the somatic region of cerebral cortex and CA_3 region of hippocampus were observed by electron microscopy. The results showed that there were no significant changes in the surface area and volume of presynaptic boutons after administration of DGAVP, in addition to the decrease of the amount of synaptic vesicles in the cortex, whereas the thickness of postsynaptic density was increased in the two brain regions of mice treated with DGAVP. These observations suggested that postsynaptic density might be of a certain importance in the DGAVP-induced synaptic plasticity for physiological events. |
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| Keywords: | DGAVP learning and memory synaptic structure |
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