| 甘油脱水酶的研究进展 |
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| 引用本文： | 王庆花,方柏山. 甘油脱水酶的研究进展[J]. 华侨大学学报(自然科学版), 2011, 32(2): 125-129 |
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| 作者姓名： | 王庆花 方柏山 |
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| 作者单位： | 1. 华侨大学,化工学院,福建,泉州,362021
2. 厦门大学化学化工学院,福建,厦门,361005 |
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| 基金项目： | 国家高技术研究发展(863)计划项目(2006AA020103); 国家自然科学基金资助项目(20446004,20676048) |
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| 摘 要： | 甘油脱水酶是微生物发酵法生产3-羟基丙醛和1,3-丙二醇过程中的关键限速酶.文中对甘油脱水酶的结构与功能、作用机制、基因工程研究等情况进行综述,探讨了甘油脱水酶的研究进展并提出一些建议.
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| 关 键 词： | 甘油脱水酶 生物转化法 结构功能 作用机制 基因工程 |
Recent Progress in Research of Glycerol Dehydratase |
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| WANG Qing-hua,FANG Bai-shan. Recent Progress in Research of Glycerol Dehydratase[J]. Journal of Huaqiao University(Natural Science), 2011, 32(2): 125-129 |
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| Authors: | WANG Qing-hua FANG Bai-shan |
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| Affiliation: | WANG Qing-hua1,FANG Bai-shan2(1.College of Chemical Engineering,Huaqiao University,Quanzhou 362021,China,(2.College of Chemistry and Chemical Engineering,Xiamen University,Xiamen 361005,China) |
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| Abstract: | Glycerol dehydratase(GDHt) is a key rate-limiting enzyme in the process of producing 3-hydroxypropionaldehyde(3-HPA) and 1,3-propanediol(1,3-PD) by microbial fermentation.In this paper,the research in the structure and functions,catalytic mechanism and genetic engineering of GDHt were reviewed.The research progresses of GDHt were also discussed and some suggestions were given in the end. |
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| Keywords: | glycerol dehydratase biotransformation structure and functions catalytic mechanism genetic engineering |
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