重庆地区冠心病危险因素分析

目的探讨重庆地区冠心病的危险因素及其与冠心病的关系,为本地区冠心病的防治和干预提供科学依据。方法选择疑似冠心病患者458例,根据临床资料和冠状动脉造影分为冠心病组和非冠心病组,分析危险因素和冠心病的关系。结果 (1)冠心病组男性、高龄、吸烟、高血压、糖尿病和血脂紊乱的比例明显高于非冠心病组(P0.05)。(2)男性冠心病组吸烟、高血压和糖尿病的比例明显高于非冠心病组(P0.05);女性冠心病组高龄、高血压和血脂紊乱明显高于非冠心病组(P0.05)。(3)低龄组冠心病男性、吸烟、高血压、糖尿病和血脂紊乱的比例显著高于非冠心病组(P0.05);高龄组冠心病高血压和糖尿病比例显著高于非冠心病组(P0.05)。结论多因素Logistic回归分析显示:年龄、性别、吸烟、高血压、糖尿病和血脂紊乱是重庆地区冠心病的最显著的危险因素。

Study on Risk Factors of Coronary Artery Disease in Chongqing

Objective To investigate the relationship between risk factors and coronary artery disease in Chong Qing and provide scientific basis for preventing and intervening coronary artery disease. Methods 458 inpatients with suspicious coronary artery disease are divided into two groups：non coronary artery disease group （ NCAD ） and coronary artery disease group （ CAD ） , according to coronary angiography to analyse the relationship between risk factors and coronary artery disease. Results （ 1 ）The rate of disease for male, who are older, smoking, and hypertensive, with abnormal lipid metabolism, is significantly higher in coronary artery disease group than that non eoronary artery disease one （P 〈 0. 05 ）. （2） In male coronary artery disease group, the rate for who are smoking and hypertensive,with diabetes mellitus, is significantly higher than that non coronary artery disease one （ P 〈 0. 05 ）. In female coronary artery disease group, the rates for who are older and hyperten- sive, with abnormal lipid metabolism,is significantly higher than that non coronary artery disease one （P 〈 0.05 ）. （3） The rates for male, who are smoking and hypertensive,with diabetes mellitus and abnormal lipid metabolism, is significantly higher in younger coronary artery disease group than that non coronary artery disease one （ P 〈 0. 05 ）. The rate for who with hypertension and diabetes mellitus is significently higher in older coronary artery disease group than that non coronary artery disease one （ P 〈 0. 05 ）. Conclusion Multiple regression analyses indicated that age, sex, smoking, hypertension, diabetes mellitus and abnormal lipid metabolism are the most prominent risk factors of coronary artery disease in Chong Qing.