Hydrolysis of histones by horse urinary kallikreins |
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| Authors: | C A M Sampaio Anis D Saad Daisy Grisolia |
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| Institution: | (1) Department of Biochemistry and Pharmacology, Escola Paulista de Medicina, C. Postal 20.372, 01000 São Paulo, S. P., (Brazil) |
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| Abstract: | Summary Horse urinary kallikrein was shown to hydrolyze histones from calf thymus and chicken nuclei erythrocytes. The hydrolysis is inhibited by benzamidine and hyposulfite but not by soy-bean trypsin inhibitor; horse plasma kallikrein also produces this hydrolysis.Work supported by grants from Projeto BIOQ/FAPESP (São Paulo), FINEP (Rio) and CNPq (Rio).Fellow from CNPq, from Instituto Biológico (São Paulo). |
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