脑出血患者肺部感染病原菌分布及易感因素分析

目的分析脑出血患者引起肺部感染的易感因素及病原菌分布。方法回顾性分析186例脑出血患者合并肺部感染的临床资料,进行肺部感染易感因素及细菌学分析。结果肺部感染的易感因素为慢性疾病糖尿病史、护理不当引起食管反流、使用≥3种抗菌药物、昏迷时间7 d、年龄60岁,差异均有统计学意义(P0.05)。共检出病原菌186株,以革兰阴性杆菌为主,占75.4%.前5位的病原菌依次是肺炎克雷伯菌、鲍曼不动杆菌、铜绿假单胞菌、金黄色葡萄球菌、大肠埃希菌,分别占22.5%,18.1%,13.4%,6.4%,5.7%,病原菌呈现较高多重耐药性。结论针对引发肺部感染的病原菌分布及易感因素进行预防和治疗,给予患者更好的护理,可降低医院肺部感染的发生和死亡率。

DISTRIBUTION OF PATHOGENIC BACTERIA CAUSING PULMONARY INFECTION AND SUSCEPTIBLE FACTORS IN PATIENTS WITH CEREBRAL HEMORRHAGE

Objectives: To investigate the distribution of pathogenic bacteria causing pulmonary infection and susceptible factors in patients with cerebral hemorrhage. Methods: Retrospective analysis on the clinical data of 186 cases of cerebral hemorrhage patients complicated with pulmonary infection was carried, the distribution of pathogenic bacteria and susceptible factors were investigated. Results: Chronic diseases diabetes, esophageal reflux caused by improper care, the use of more than 3 kinds of antibiotics, coma time >7d and age (> 60 years old) were susceptible factors for pulmonary infection; the differences were statistically significant ( all P < 0.05). There were 186 strains of pathogenic bacteria, the most common pathogen was Gram-negative bacilli which accounted for 75.4%, followed by Klebsiella pneumoniae (22.5%), Acinetobacter baumannii (18.1%), Pseudomonas aeruginosa (13.4%), Staphylococcus aureus (6.4%), Escherichia coli (5.7%). Pathogenic bacteria showed high multiple drug resistance. Conclusion: It is necessary to strengthen the prevention and treatment in accordance with the distribution of pathogenic bacteria causing pulmonary infection and susceptible factors, better care for patients, which can reduce the incidence of pulmonary infection and mortality in hospital.