| 抗原对CD8+T细胞记忆的贡献 |
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| 引用本文： | 毛理凯,漆安慎.抗原对CD8+T细胞记忆的贡献[J].北京师范大学学报(自然科学版),2001,2(1):66-71. |
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| 作者姓名： | 毛理凯 漆安慎 |
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| 作者单位： | 北京师范大学物理学系，100875，北京 |
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| 基金项目： | 国家自然科学基金资助项目(30070216) |
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| 摘 要： | 基于T细胞的逆线性分化假说建立了非线性理论模型，利用此模型，得出记忆T细胞逆线性分化模型确有记忆机制，并发现记忆强度与抗原量有直接的关系。
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| 关 键 词： | 免疫 T细胞记忆 细胞分化 逆线性一分化模型 CD8^＋T细胞 记忆机制 记忆强度 抗原量 |
| 修稿时间： | 2000年9月4日 |
CONTRIBUTIONS OF ANTIGEN TO MAINTENANCE OF CD8+T CELL MEMORY |
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| Mao Likai.CONTRIBUTIONS OF ANTIGEN TO MAINTENANCE OF CD8+T CELL MEMORY[J].Journal of Beijing Normal University(Natural Science),2001,2(1):66-71. |
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| Authors: | Mao Likai |
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| Abstract: | It is still debated how T cell memory is maintained. Based on theconverse linear differentiation hypothesis of memory T cells, a nonlinear theoretical model is established. This model demonstrated that there exists memory mechanism on the basis of converse linear differentiation hypothesis. In the present paper, “memory strength” is introduced and the relationship between memory strength and residual antigenic doses has been studied. |
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| Keywords: | immunity mathematical model antigen T cell memory cell differentiation |
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