Differential alterations in branched-chain amino acid decarboxylation in liver of hypophysectomized rats |
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| Authors: | S. G. Sullivan Dorothy A. Potter Marjorie R. Krauss J. Dancis R. P. Cox |
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| Affiliation: | (1) Division of Human Genetics, Departments of Medicine, Pharmacology and Pediatrics, New York University Medical Center, 550 First Avenue, 10016 New York, New York, USA |
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| Abstract: | ![]()
Summary Valine decarboxylation was significantly increased and leucine decarboxylation was significantly decreased in rat liver slices following hypophysectomy. In both normal and hypophysectomized rats decarboxylation of leucine exceeded that of valine in slices whereas the reverse was observed with the respective keto acids and mitochondria.Acknowledgments. This study was supported by the National Institutes of Health and the Samuel A. Berger Foundation. |
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