| 抗变态反应平喘新药氮斯汀~1H和~(13)C NMR谱线的归属 |
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| 引用本文： | 李文,吴立军,钟大放,漆新国,张新华,刘丽.抗变态反应平喘新药氮斯汀~1H和~(13)C NMR谱线的归属[J].辽宁大学学报(自然科学版),1999(2). |
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| 作者姓名： | 李文 吴立军 钟大放 漆新国 张新华 刘丽 |
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| 作者单位： | 沈阳药科大学，沈阳市卫生防疫站 |
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| 摘 要： | 用１Ｄ（ＮＯＥ差谱、ＤＥＰＴ谱）和２ＤＮＭＲ技术（ＨＨＣＯＳＹ、ＨＭＱＣ和ＨＭＢＣ）归属了合成抗变态反应平喘新药氮卓艹斯汀两种异构体的１Ｈ和１３ＣＮＭＲ谱线
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| 关 键 词： | 氮斯汀 2DNMR 异构体 |
The NMR Study of the Antiallergic and Antiasthmatic Agent Azelastine |
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| LI Wen WU Lijun ZHONG Dafang QI Xinguo ZHANG Xinhua Shenyang Pharmaceutical University,Shenyang LIU Li Shenyang Sanitation Anti epidemic Station,Shenyang.The NMR Study of the Antiallergic and Antiasthmatic Agent Azelastine[J].Journal of Liaoning University(Natural Sciences Edition),1999(2). |
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| Authors: | LI Wen WU Lijun ZHONG Dafang QI Xinguo ZHANG Xinhua Shenyang Pharmaceutical University Shenyang LIU Li Shenyang Sanitation Anti epidemic Station Shenyang |
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| Institution: | LI Wen WU Lijun ZHONG Dafang QI Xinguo ZHANG Xinhua Shenyang Pharmaceutical University,Shenyang 110015 LIU Li Shenyang Sanitation Anti epidemic Station,Shenyang 110031 |
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| Abstract: | Total assignment of 1H and 13 C NMR spectrallines of the synthesized antiallergic and antiasthematic agent Azelastine which are two isomers, has been accomplished by ID(NOE difference and DEPT) and 2D NMR techniques (HHCOSY, HMQC and HMBC). |
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| Keywords: | Azelastine 2DNMR isomer |
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