The effect of cyclic AMP on Na+ and K+ transport systems in mouse macrophages |
| |
| Authors: | J. Diez P. Braquet R. Verna C. Nazaret R. P. Garay |
| |
| Affiliation: | (1) INSERM U7/CNRS LA 318, Hopital Necker, 161 rue de Sevres, F-75015 Paris, (France);(2) Present address: IHB, 17 avenue Descartes, F-92000 Le Plessis-Robinson, France |
| |
| Abstract: | ![]()
Summary Exogenous cyclic AMP (cAMP) inhibits the Na+, K+-cotransport system and stimulates the Na+, K+-pump and Na+, Ca2+ exchange in mouse macrophages. These effects are enhanced by inhibition of phosphodiesterase with methylisobutylxanthine (MIX). MIX alone showed little or no effect. A similar response was observed after stimulation of endogenous production of cAMP by isoproterenol. |
| |
| Keywords: | Na+ K+ transport macrophages cyclic AMP mouse |
| 本文献已被 SpringerLink 等数据库收录！ |
|
