| 多壁碳纳米管修饰丝印电极的制备及在尿酸测定中的应用 |
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| 引用本文： | 周娟,刘敏. 多壁碳纳米管修饰丝印电极的制备及在尿酸测定中的应用[J]. 兰州大学学报(自然科学版), 2009, 45(3) |
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| 作者姓名： | 周娟 刘敏 |
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| 作者单位： | 上海电力学院能源与环境工程学院,上海,200090;武汉大学药学院,武汉,430072 |
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| 摘 要： | 利用丝网印刷技术制作一次性使用的丝印碳糊电极,采用吸附法将羧基化的多壁碳纳米管修饰在电极表面,建立测定尿酸的简单快捷的电化学分析方法.将该法用于全血尿酸的测定,在pH7.4的磷酸盐缓冲溶液中,测定尿酸的伏安行为,多壁碳修饰电极比裸电极具有更好的选择性和更高的灵敏度.差示脉冲伏安法测得尿酸浓度在2～100μmol/L范围内,峰电流值与浓度呈线性,相关系数为0.9979,检测限为1.0μmol/L.在全血样本中,加入0～0.4 mmol/L的尿酸溶液,线性相关系数为0.9975.该方法简单、快速,电极制作成本低,所需仪器简单,样品不需预处理,用于全血尿酸的测定结果满意,可作为一次性测试条使用,为尿酸检测走入小型化、家庭化提供了实验基础.
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| 关 键 词： | 多壁碳纳米管 丝印电极 尿酸 全血 示差脉冲伏安法 |
Preparation of multi-walled carbon nanotube modified screen printed electrode and its application in uric acid determination |
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| ZHOU Juan,LIU Min. Preparation of multi-walled carbon nanotube modified screen printed electrode and its application in uric acid determination[J]. Journal of Lanzhou University(Natural Science), 2009, 45(3) |
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| Authors: | ZHOU Juan LIU Min |
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| Affiliation: | 1.Energy and Environment Engineering Institute;Shanghai University of Electric Power;Shanghai 200090;China;2.College of Pharmacy;Wuhan University;Wuhan 430072;China |
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| Abstract: | The one-off screen printed carbon paste electrode was prepared using screen printing technology. Carboxylic multi-walled carbon nanotubes were absorbed on the working surface of screen printed electrode, which proved to be a simple and rapid electrochemical analysis method of uric acid determination.The assay was applied to the determination of uric acid in whole blood.The electrocatalytic response of uric acid on the modified screen printed electrode was evaluated by cyclic voltammetry in a 0.1 mol/L phosp... |
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| Keywords: | multi-walled carbon nanotube screen printed electrode uric acid blood differential pulse voltammetry |
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