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知柏地黄丸浸液对大鼠嗜铬细胞内钙的作用
引用本文:叶琴,陈良怡,张春光,周专. 知柏地黄丸浸液对大鼠嗜铬细胞内钙的作用[J]. 华中科技大学学报(自然科学版), 2000, 28(6): 108-110
作者姓名:叶琴  陈良怡  张春光  周专
作者单位:华中理工大学生命科学与技术学院;华中理工大学生命科学与技术学院;华中理工大学生命科学与技术学院;华中理工大学生命科学与技术学院
基金项目:国家自然科学基金项目(69671007)
摘    要:运用Fura-2显微荧光测量技术,在单个大鼠肾上腺嗜铬细胞上,测量中药知柏地黄丸浸液对胞内游离钙浓度([Ca

关 键 词:知柏地黄丸浸液  嗜铬细胞  胞内游离钙浓度
文章编号:1000-8616(2000)06-0108-03
修稿时间:1999-12-14

The Effects of Extract of Zhi Bo Di Huang Wan on the [Ca2+]i of Rat Chromaffin Cell
Ye Qin,Chen Liangyi,ZHANG ChunGuang,ZHOU Zhuan. The Effects of Extract of Zhi Bo Di Huang Wan on the [Ca2+]i of Rat Chromaffin Cell[J]. JOURNAL OF HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY.NATURE SCIENCE, 2000, 28(6): 108-110
Authors:Ye Qin  Chen Liangyi  ZHANG ChunGuang  ZHOU Zhuan
Abstract:By using microflurescent calcium measurement technique, the effects of extract of Zhi Bo Di Huang Wan on the intracellular calcium concentration ([Ca 2 ] i) of single rat Chromaffin cell were studied. The results showed the extract caused an increase of [Ca 2 ] i when it was puffing to the cell. Removing Ca 2 from the bath solution or nifedipine obviously inhibited the increasement of [Ca 2 ] i induced by the extract. It illustrated that the dependence of the Zhi Bo Di Huang triggered calcium signal on extracellular Ca 2 and the opening of L Ca 2 Channel made a great contribution to the [Ca 2 ] i increase.
Keywords:extract of Zhi Bo Di Huang  chromaffin cell  intracellular calcium concentration
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