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| 铜代谢紊乱对脑神经系统疾病的影响 | |
| 引用本文： | 李琦,张源,易美芝,刘少文,庄东红,吴仁华,陈耀文.铜代谢紊乱对脑神经系统疾病的影响[J].汕头大学学报(自然科学版),2012,27(3):54-60. |
| 作者姓名： | 李琦 张源 易美芝 刘少文 庄东红 吴仁华 陈耀文 |
| 作者单位： | 1. 汕头大学理学院,广东汕头,515063 2. 汕头大学医学院,广东汕头,515041 3. 潮州师范学院,广东潮州,521041 |
| 基金项目： | 国家自然科学基金资助项目，广东省自然科学基金，汕头大学科研启动基金资助项目 |
| 摘 要： | 铜是维持哺乳动物正常生理活动的微量元素,体内铜的含量与细胞呼吸、自由基防御、血管生成、神经细胞和机体的生长发育有密切关系,它还参与脑生理活动的调节.体内铜的含量、转运及分布都受到精密的调控,铜元素缺乏和过量时都严重影响机体健康.铜及铜相关酶生物系统中对生命过程有着重要的作用,其代谢异常往往会导致严重的神经症状和神经系统疾病.本文将综述铜代谢紊乱对脑神经系统疾病的影响. |
| 关 键 词： | 铜代谢 神经系统疾病 神经受体 |
Effects of Copper Metabolism Disorders on Brain Nervous System Diseases |
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| LI Qi,ZHANG Yuan,YI Mei-zi,LIU Shao-wen,ZHUANG Dong-hong,WU Ren-hua,CHEN Yao-wen.Effects of Copper Metabolism Disorders on Brain Nervous System Diseases[J].Journal of Shantou University(Natural Science Edition),2012,27(3):54-60. | |
| Authors: | LI Qi ZHANG Yuan YI Mei-zi LIU Shao-wen ZHUANG Dong-hong WU Ren-hua CHEN Yao-wen |
| Institution: | 1.Science College of Shantou University,Shantou 515063,Guangdong,China; 2.Medical College of Shantou University,Shantou 515041,Guangdong,China; 3.Chaozhou Normal College,Chaozhou 521041,Guangdong,China) |
| Abstract: | Copper(Cu) is an essential trace element for mammalian physiological activities.Copper is closely allied with cellular respiration,free radical defense,angiogenesis,the development of neurocyte and body.Some brain physiological functions are known to be copper-dependent.The concentration,transport and distribution of copper are subjected to precise regulation in the body.Copper deficiency or excess may lead seriously diseases.Copper and cuproenzymes play an important role in mammalian,copper metabolism disorder may cause severe neurological symptoms and neurological diseases.The relation of copper metabolism disorders and neurological diseases is briefly discussed. |
| Keywords: | copper metabolism nervous system disease nerve receptor |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |