Prostaglandin (15S)-PGA2 derivatives in the gorgonianPlexaura homomalla (Esper), formakükenthali Moser |
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Authors: | L S Ciereszko Y Gopichand F J Schmitz W P Schneider G L Bundy |
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Institution: | (1) Chemistry Department, The University of Oklahoma, 73019 Norman, Oklahoma, USA;(2) The Upjohn Company, 49001 Kalamazoo, Michigan, USA |
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Abstract: | Summary The lipid fraction, 17%, of air-driedPlexaura homomalla formakükenthali, collected in the Caribbean at Puerto Rico, yielded 50% of its weight as the mammalian prostaglandin (15S)-PGA2 methyl ester. The freeze-dried gorgonian yielded (15S)-PGA2 largely as the acetate of the methyl ester. (15S)-PGA2 was also obtained from material collected at St. Croix and at South Caicos. Field observations indicate thatPlexaura kükenthali may be a species separate fromPlexaura homomalla and that it is abundant on some shallow water reefs in the Caribbean. Prostaglandins could not be detected in the lipid fraction of eggs isolated fromPlexaura homomalla (Esper) formahomomalla.Acknowledgments. We gratefully acknowledge support from the Office of Sea Grant, NOAA, Department of Commerce (Grant 047-158-44067), and the use of facilities at the Isla Mayagues Marine Laboratory of the University of Puerto Rico, Mayaguez, the West Indies Laboratory of Fairleigh Dickinson University at St. Croix, U.S.V.I., and the Marine-Biologisch Instituut at Curacao. Special thanks to Dr. F.M. Bayer, Curator, Department of Zoology, National Museum of Natural History-Smithsonian Institution for checking identity of gorgonians used in this study. |
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Keywords: | Gorgonia Plexaura homomalla prostaglandins |
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