Zum Proliferations-Stoffwechsel der Rattenleber nach Teilhepatektomie. Autoradiographische Untersuchungen mit3H-Cytidin,-Phenylalanin und -Thymidin |
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| Authors: | E Stöcker W Liebscher H -W Altmann |
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| Institution: | (1) Pathologisches Institut der Universität Würzburg, Deutschland |
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| Abstract: | Summary During the first wave of parenchymal liver regeneration in adult rats after partial hepatectomy, the cellular synthesis and migration of RNA and the metabolism of protein were studied by autoradiography following an injection of3H-cytidine or3H-l-phenylalanine and double injections of 1 of these precursors +3H-thymidine. The following results were obtained: the synthesis and migration of RNA and the metabolism of protein are enhanced under these conditions of proliferation. In spite of this, the relation of metabolic activity in nucleolus, karyoplasm and cytoplasm remains constant. By double injection techniques it is proved that no differences exist in migration of RNA into the cytoplasm and cytoplasmic protein synthesis between cells with or without DNA synthesizing nuclei.
Mit Unterstützung der Deutschen Forschungsgemeinschaft. |
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