Regional distribution of thiamin pyrophosphokinase in rat brain |
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| Authors: | T. Matsuda Y. Yabushita T. Doi H. Iwata |
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| Affiliation: | (1) Department of Pharmacology, Faculty of Pharmaceutical Sciences, Osaka University, 1-6 Yamadaoka, 565 Suita, Osaka, (Japan) |
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| Abstract: | ![]()
Summary The highest specific activity of thiamin pyrophosphokinase was found in the cerebellum, and lower activity in cerebral cortex and midbrain. The regional difference in the enzyme activity was similar to that in thiamin content and the influx rate in rat brain, suggesting that the enzyme is involved in the thiamin transport. |
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| Keywords: | Thiamin thiamin pyrophosphokinase cerebellum |
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