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Deficits in social behavior in autism and their modification by a synthetic adrenocorticotrophic hormone (4–9) analog |
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| Authors: | J. K. Buitelaar H. van Engeland C. H. de Kogel H. de Vries J. A. R. A. M. van Hooff J. M. van Ree |
| Affiliation: | (1) Department of Child and Adolescent Psychiatry, Utrecht University Hospital, P.O. Box 85 500, NL-3508 GA Utrecht, (The Netherlands);(2) Department of Ethology and Socio-ecology, Utrecht State University, P.O. Box 80 086, NL-3508 TB Utrecht, (The Netherlands);(3) Rudolf Magnus Institute, Utrecht State University, Vondellaan 6, NL-3521 GD Utrecht, (The Netherlands) |
| Abstract: | When charting the structure of the social behavior of autistic children by means of an ethologically analyzed playroom session, deficits appeared in the reciprocity of eye-contact and in the location of verbal initiatives. These deficits in social behavior were beneficially influenced by treatment with the adrenocorticotrophic hormone (4–9) analog ORG 2766. |
| Keywords: | Social behavior neuropeptides ethology autism |
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