| Synthesis of L-cystine bridged bis(p-cyclodextrin) and its cooperative binding toward guest molecules |
| |
| 作者姓名： | LI Li LI Xiaoyun & LIU Yu |
| |
| 作者单位： | LI Li，LI Xiaoyun & LIU Yu
Department of Chemistry，State Key Laboratory of Elemento-Organic Chemistry，Nankai University，Tianjin 300071，China |
| |
| 摘 要： | A novel p-cyclodextrin derivative, L-cystine bridged bis(β-cyclodextrin) 1 has been synthesized and characterized by 1H NMR, 13C NMR, IR, Raman and combustion analyses. Spectrofluorometric titrations have been performed in aqueous phosphate buffer solution (pH=7.20) at 25℃ to give the complex stability constants (Ks) and Gibbs free energy changes (-△G°) for the stoichiometric 1 : 1 inclusion complexation of 1 with four dyes. The binding abilities and molecular selectivities are discussed from the viewpoint of size/shape-fit and electrostatic interactions between hosts and guests. 2D ROESY investigation for the complexation between host and guest further confirms the cooperative binding of bridged cyclodextrin 1 with guest.
|
Synthesis of L-cystine bridged bis(p-cyclodextrin) and its cooperative binding toward guest molecules |
| |
| LI Li,LI Xiaoyun & LIU Yu.Synthesis of L-cystine bridged bis(p-cyclodextrin) and its cooperative binding toward guest molecules[J].Chinese Science Bulletin,2004(2). |
| |
| Authors: | LI Li LI Xiaoyun & LIU Yu |
| |
| Institution: | LI Li,LI Xiaoyun & LIU Yu
Department of Chemistry,State Key Laboratory of Elemento-Organic Chemistry,Nankai University,Tianjin 300071,China |
| |
| Abstract: | |
| |
| Keywords: | L-cystine birdged bis(cyclodextrin) dye cooperative binding |
| 本文献已被 CNKI 等数据库收录！ |
