Genomic segmental polymorphisms in inbred mouse strains |
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| Authors: | Li Jiangzhen Jiang Tao Mao Jian-Hua Balmain Allan Peterson Leif Harris Charles Rao Pulivarthi H Havlak Paul Gibbs Richard Cai Wei-Wen |
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| Institution: | Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030, USA. |
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| Abstract: | By analyzing genomic copy-number differences using high-resolution mouse whole-genome BAC arrays, we uncover substantial differences in regional DNA content between inbred strains of mice. The identification of these apparently common segmental polymorphisms suggests that these differences can contribute to genetic variability and pathologic susceptibility. |
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