A novel antagonist of serotonergic receptors,hymenidin, isolated from the Okinawan marine spongeHymeniacidon sp. |
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Authors: | J. Kobayashi Y. Ohizumi H. Nakamura Y. Hirata |
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Affiliation: | (1) Mitsubishi-Kasei Institute of Life Sciences, 11 Minamiooya, 194 Machida, Tokyo, (Japan);(2) Faculty of Pharmacy, Meijo University, 468 Nagoya, (Japan) |
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Abstract: | ![]() Summary A novel bromine-containing pyrrole compound, hymenidin, has been isolated from the Okinawan marine spongeHymeniacidon sp. as a potent antagonist of serotonergic receptors and its structure elucidated using spectral data. |
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Keywords: | Sponge hymenidin Hymeniacidon sp. bromopyrrole antiserotonergic action |
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